PAF受体拮抗剂,PAF receptor antagonist
1)PAF receptor antagonistPAF受体拮抗剂
1.Objective: To search for novel potent compounds withPAF receptor antagonistic and iNOS inhibitory activities for the treatment of septic shock.方法 :以PAF受体拮抗剂 2 ,4 -二芳基 -1 ,3-二硫戊环化合物为先导物 ,在其结构中引入有抑制 i NOS活性的异硫脲基并测定目标化合物的 i NOS抑制活性。
英文短句/例句
1.Effects of Intrathecal Injection with PAF Receptor Antagonists on Behavior and c-fos Expression in Spinal Cord of Rats with Spinal Nerve Ligation鞘内注射PAF受体拮抗剂对SNL大鼠痛敏和脊髓c-fos表达的影响
2.Effect of PAF antagonist on NO content and expression of iNOS in gastric mucosal during endotoxemia in young ratsPAF受体拮抗剂对内毒素血症幼年大鼠胃黏膜NO含量及iNOS表达的影响
3.Study of Cytoprotection of Gastric Mucosal and Intervention by Platelet Activating Factor Receptor Antagonist during Endotoxemia in Baby Rats;内毒素血症幼年大鼠胃黏膜细胞保护作用及PAF受体拮抗剂干预的研究
4.Relationship between Effect and Dosage of NMDA Receptor AntagonistNMDA受体拮抗剂作用与剂量的关系
5.3D-QSAR Studies on GABA_A Receptor Noncompetitive Antagonists;GABA_A受体非竞争性拮抗剂的3D-QSAR研究
6.The Ionic Mechanism of Securinine as the GABA_A Receptor Antagnist;Securinine作为GABA_A受体拮抗剂的离子作用机制
7.Design and Synthesis of Selective M3 Receptor Antagonists选择性M3受体拮抗剂的设计与合成
8.The Synthesis of a Novel CC Chemokine Receptor 2 Antagonist新型趋化因子受体CCR2拮抗剂的合成
9.Receptor Antagonist of NMDA and Animal Models of SchizophreniaNMDA受体拮抗剂与精神分裂症动物模型
10.Design, Synthesis and Anti-activities Study of Phenylurea Histamine H_3 Antagonists;苯脲类组胺H_3受体拮抗剂的设计、合成和拮抗活性研究
11.Anti-Inflammatory Effect of Angiotensin Receptor 1 Blockers (ARBS) and Its Mechanism;血管紧张素受体拮抗剂抗炎症作用及机制研究
12.Study on the New Anti-Ulcer Complexes of H_2-Receptor Antagonists and Zinc;抗溃疡新药H_2受体拮抗剂锌盐配合物的研究
13.Study on Diastereoselective Synthesis of Chiral M Receptor Antagonists;M受体手性拮抗剂的立体选择性合成研究
14.Neuroprotective role of antagonist of platelet active factor receptor血小板活化因子受体拮抗剂的神经保护作用
15.Amiodarone also acts as a thyroid hormone receptor antagonist.胺碘酮也可作为甲状腺激素受体拮抗剂。
16.Synthetic Research of Aldosterone Receptor Antagonist Eplerenone;醛固酮受体拮抗剂依普利酮的合成工艺研究
17.Design and Synthesis of a New Series of the Angiotensin Ⅱ Receptor Antagonists;新型血管紧张素Ⅱ受体拮抗剂的设计与合成
18.Studies on a New H_1-Receptor Antagonist Mizolastine;新型H_1受体拮抗剂咪唑斯汀的合成工艺研究
相关短句/例句
Receptor antagonist受体拮抗剂
1.Advances on leukotrienes and leukotriene receptor antagonists in asthma;白三烯受体拮抗剂研究新进展
2.Eplerenone——a new aldosterone receptor antagonist with cardiovascular protective effect;对心血管具有保护作用的醛固酮受体拮抗剂依普利酮
3.Anti-asthmatic effects of interleukin-1 receptor antagonist in sensitized guinea pigs;白介素-1受体拮抗剂对致敏豚鼠的抗喘作用(英文)
3)5-HT3 receptor antagonist5-HT3受体拮抗剂
1.Ondansetron Hydrochloride is a high effective and high selective5-HT3 receptor antagonist and is used on anti-emesis after chemotherapy and radiotherapy and postoperation.盐酸昂丹司琼（Ondansetron Hydrochloride）是一种高效，高选择性的5-HT3受体拮抗剂[1,2]，用于对抗癌症化学治疗和放射治疗引起的呕吐以及手术后的急性呕吐[3-5]。
4)AT1 receptor antagonistAT1受体拮抗剂
1.Objective To investigate the effects ofAT1 receptor antagonist candesartan on acute pancreatitis(AP) of rats.结论早期应用AT1受体拮抗剂坎地沙坦可以明显减轻大鼠胰腺的急性炎症病变及损伤。
5)NMDA receptor antagonistNMDA受体拮抗剂
1.objective The effect was investigated to induce NSC proliferation and differentiation in the adult rat SGZ、SVZ and cortex byNMDA receptor antagonist administration following focal ischemic insults produced by middle cerebral artery occlusion (MCAO).结论NMDA受体拮抗剂MK- 80 1在脑缺血后,能促进NSC的增殖、分化。
2.Investigation of Internal Activating Neural Stem Cell by NMDA Receptor Antagonist Administration Following Focal Ischemic Insults;结论:NMDA受体拮抗剂MK801在脑缺血后,能促进大鼠海马区NSCs的增殖、分化。
6)H1-receptor antagonistH1-受体拮抗剂
延伸阅读
钙拮抗剂钙拮抗剂calciumantagonists主要通过阻断心肌和血管平滑肌细胞膜上的钙离子通道，抑制细胞外钙离子内流，使细胞内钙离子水平降低而引起心血管等组织器官功能改变的药物。临床常用的有硝苯吡啶、异搏定、硫氮唑酮等。对心脏的作用，主要是抑制心肌去极化过程中第二时相钙离子内流，降低细胞内钙，减弱心肌收缩力，降低心肌氧耗量，同时抑制窦房结和房室结的钙内流，使窦房结自律性下降，房室传导减慢，心室率降低，如异搏定，硫氮唑酮。在血管主要扩张动脉平滑肌，降低外周阻力，而对静脉平滑肌作用甚小，如硝苯吡啶。此类药物临床主要应用于高血压病、冠心病和心律失常。
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