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Maternal Use of Selective Serotonin Reuptake Inhibitors and Lengthening of the Umbilical Cord: Indirect Evidence of Increased Foetal Activity—A Retrospective Cohort Study
Julia Kivist et al.
Umbilical cords of children whose mothers used selective serotonin reuptake inhibitors during pregnancy may be longer than umbilical cords of other newborn children, shows a new study from the University of Eastern Finland and Kuopio University Hospital. Selective serotonin reuptake inhibitors, SSRIs, are commonly prescribed antidepressants, and this is the first time their association with umbilical cord length was observed. The findings were published in PLOS ONE. A long umbilical cord can weaken foetal circulation and expose the foetus to a lack of oxygen during the pregnancy or birth, among other things. According to the study researchers, this newly observed association of prenatal SSRI use with umbilical cord length may indicate that SSRI drugs increase foetal activity and movement in the uterus. The length of the umbilical cord is affected by how much the growing foetus moves in the uterus. "When the foetus moves, the umbilical cord stretches and eventually gets longer," says PhD student Julia Kivist , the first author of the study.
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